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Top Santa Cruz hotels

Hotel Boutique Grand Cru
Chomedahue, cruce El Guindo Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $92 total per night from Nov 11 to Nov 12
$92 total
Nov 11 - Nov 12
This hotel features an outdoor pool and a gym. Enjoy the steam room and free perks like continental breakfast and free self parking. A business center, free ...
"Great breakfast. Super host Juan Luis. Great location. Comfy bed. Spacious loft style rooms"
Reviewed on Mar 29, 2026

Hotel Vendimia Parador
Camino Los Boldos SN Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $116 total per night from Dec 2 to Dec 3
$116 total
Dec 2 - Dec 3
This hotel features an outdoor pool and an indoor pool. Relax with a drink at the swim-up bar and enjoy perks like free self parking and free WiFi. Free parking, ...
"A bit outdated with lots of old furnishings. Beautiful place with friendly owners and beautiful gardens"
Reviewed on Nov 3, 2026

TerraViña
Camino Los Boldos S/n Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$300 nightly
The price is $300 total per night from Nov 16 to Nov 17
$300 total
Nov 16 - Nov 17
An attached winery and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."
Reviewed on Aug 7, 2026

Santa Cruz Plaza
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $115 total per night from Dec 6 to Dec 7
$115 total
Dec 6 - Dec 7
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate the free kid's club, barbecue grills, ...
"The service from the staff is immaculate. The properly full of charm and character. The rooms are spacious, clean and comfortable"
Reviewed on Nov 3, 2026

Hotel Cava Colchagua
Barreales´s Way Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $135 total per night from Nov 15 to Nov 16
$135 total
Nov 15 - Nov 16
This hotel features an attached winery, a full-service spa, and a restaurant. Enjoy the outdoor pool and free perks like local cuisine breakfast and WiFi in ...
"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría ..."
Reviewed on Aug 7, 2026

Hotel Boutique Vendimia Premium
Ismael Valdes 92 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $71 total per night from Nov 9 to Nov 10
$71 total
Nov 9 - Nov 10
A seasonal outdoor pool, free self parking, and free newspapers are featured at this hotel. WiFi in public areas is free. A terrace, a garden, and a lobby fireplace ...

La Perla Hotel
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
This hotel features a seasonal outdoor pool and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and airport ...

Colchagua Tiny Lodge
I-350 kilometro 4,5 Santa Cruz O'Higgins
$184 nightly
The price is $184 total per night from Nov 9 to Nov 10
$184 total
Nov 9 - Nov 10
This cabin features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free local cuisine breakfast each morning. A terrace, a garden, ...

Casa Calfu
21 de Mayo 552 Santa Cruz OHiggins
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $78 total per night from Nov 11 to Nov 12
$78 total
Nov 11 - Nov 12
An outdoor pool, free self parking, and laundry facilities are featured at this bed & breakfast. Guests will appreciate free perks like buffet breakfast and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Santa Cruz hotel reviews by fellow wanderers

Santa Cruz Plaza
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"The service from the staff is immaculate. The properly full of charm and character. The rooms are spacious, clean and comfortable"
A verified traveler stayed at Santa Cruz Plaza
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